Mapping the human brain is one of the great scientific challenges of the 21st century. The Human Connectome Project (HCP) is tackling a key aspect of this challenge by elucidating the neural pathways that underlie brain function and behavior. Deciphering this amazingly complex wiring diagram will reveal much about what makes us uniquely human and what makes every person different from all others.
The consortium led by Washington University, University of Minnesota, and Oxford University (the WU-Minn HCP consortium) is comprehensively mapping human brain circuitry in a target number of 1200 healthy adults using cutting-edge methods of noninvasive neuroimaging. It will yield invaluable information about brain connectivity, its relationship to behavior, and the contributions of genetic and environmental factors to individual differences in brain circuitry and behavior.
Starting with the first quarterly (Q1) data release (March, 2013), HCP datasets are being made freely available to the scientific community. Four imaging modalities are used to acquire data with unprecedented resolution in space and time. Resting-state functional MRI (rfMRI) and diffusion imaging (dMRI) provide information about brain connectivity. Task-evoked fMRI reveals much about brain function. Structural MRI captures the shape of the highly convoluted cerebral cortex. Behavioral data provides the basis for relating brain circuits to individual differences in cognition, perception, and personality. In addition, 100 participants will be studied using magnetoencephalography and electroencephalography (MEG/EEG).
Successful charting of the human connectome in healthy adults will pave the way for future studies of brain circuitry during development and aging and in numerous brain disorders. In short, it will transform our understanding of the human brain in health and disease.
The latest version of Connectome Workbench was released on Nov 21, and is now available for download. Get Workbench
The Connectome-in-a-Box storefront is now open. Get data for up to 232 subjects on a set of pre-formatted Linux hard drives. Learn More
Q3 imaging and behavioral data has been released, including updated diffusion imaging, individual task analysis, and improved denoising. Register to get access.
HCP will have a prominent presence at the Organization for Human Brain Mapping conference in Seattle, from June 16-20. HCP at OHBM 2013.
MEG study uses multivariate interaction measures to capture interactions within and across resting state networks over time. Read more.
New SENSE image reconstruction method reduces the noise floor in diffusion tractography. Read More.
"Snowball" sampling method identifies cortical areas that make up functional connectivity networks in individuals. Read More.
To protect its participants' identities, the HCP restricts access to some of its data. Which set of data use terms is right for your research? Learn More.
MEG study shows temporal dynamics of resting state network interactions. Read more.