Workbench Command is a set of command-line tools that can be used to perform simple and complex operations within Connectome Workbench.
DO TFCE ON A VOLUME FILE wb_command -volume-tfce <volume-in> - the volume to run TFCE on <volume-out> - output - the output volume [-presmooth] - smooth the volume before running TFCE <kernel> - the size of the gaussian smoothing kernel in mm, as sigma by default [-fwhm] - smoothing kernel size is FWHM, not sigma [-roi] - select a region of interest to run TFCE on <roi-volume> - the area to run TFCE on, as a volume [-parameters] - set parameters for TFCE integral <E> - exponent for cluster volume (default 0.5) <H> - exponent for threshold value (default 2.0) [-subvolume] - select a single subvolume <subvolume> - the subvolume number or name Threshold-free cluster enhancement is a method to increase the relative value of regions that would form clusters in a standard thresholding test. This is accomplished by evaluating the integral of: e(h, p)^E * h^H * dh at each vertex p, where h ranges from 0 to the maximum value in the data, and e(h, p) is the extent of the cluster containing vertex p at threshold h. Negative values are similarly enhanced by negating the data, running the same process, and negating the result. This method is explained in: Smith SM, Nichols TE., "Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference." Neuroimage. 2009 Jan 1;44(1):83-98. PMID: 18501637