Archived Data Releases
PDC 1.0 Release Released on 03/30/2023
PDC Release 1.0 of imaging and behavioral data is now available in the NIMH Data Archive (NDA). Perturbation of the depression connectome by fast-acting therapies (Perturbation of the Depression Connectome, PDC) is a study of adults with and without treatment resistant depression (191 patients, 39 controls) and with and without fact-acting treatment interventions (ages 20-64, with treatment-resistant depression treated with ECT [N=44], ketamine [N=67], or total sleep deprivation [N=80], plus healthy controls [N=39]).
PDC Release 1.0 data includes:
- unprocessed data of all modalities (structural MRI, resting state fMRI, task fMRI for 3 tasks, and diffusion MRI) for 227 subjects
- minimally preprocessed MRI data of all modalities for up to 218 subjects
- clinical and behavioral data for 230 subjects
Get Access and Download the data: Get started with the Data Access and Download Instructions for obtaining access, navigating NDA and using it's download tools. We've also created a wiki that details setup steps for downloading data via NDA's command line tools.
The released data are available on NDA as:
- PDCRec package of recommended preprocessed + behavioral data (1076 GB, OPTION ONE)
- PDCAllFiles package of all released imaging and behavioral data (9.5 TB, OPTION ONE)
- PDCImgManifestBeh package of imaging manifests + behavioral data (332 MB, OPTION ONE)
- or can be filtered on to create a custom package of a subset of the data (OPTION TWO).
Want more information? Check out our documentation to help with understanding the project and interpreting the data.
View Data Release Documentation
Release Date: Mar 30, 2023