Perturbation of the Treatment of Resistant Depression Connectome by Fast-Acting Therapies (PDC)

PDC 1.0 Release

Release Date: Apr 27, 2023
Type: Data Release

PDC Release 1.0 data is now available in the NIMH Data Archive (NDA). All PDC (ages 20-64, with treatment-resistant depression treated with ECT, ketamine, or total sleep deprivation, plus healthy controls) data is shared in NDA Collection #2844.


PDC Release 1.0 data includes: 

  • unprocessed imaging data of all modalities (structural MRI, resting state fMRI, task fMRI, diffusion MRI, and arterial spin labeling) for up to 227 subjects
  • minimally preprocessed MRI data (structural MRI, resting state fMRI, task fMRI, and diffusion MRI) for up to 218 subjects
  • clinical and behavioral data for 230 subjects


Full details of the project and released data are available in the: 


Get Access and Download the data: Get started with the Data Access and Download Instructions for getting access, navigating NDA, and using it's download tools. We've also created a wiki that details setup for downloading data via NDA's command line tools.