Human Connectome Project for Early Psychosis

Imaging Protocols for HCP-Early Psychosis

HCP-EP's imaging protocols are based on the 2016 CCF template protocol with a total duration of approximately 70 minutes. HCP-EP collected data on three Siemens MAGNETOM Prisma 3T scanners at BWH, McLean, and IU. BWH and IU used a 32-channel head coil. The McLean used a 64-channel head & neck coil, with the neck channels turned off. 

In short, the protocol scan sequences were:

  • T1w (MPRAGE) and T2w (SPACE) structural scans of 0.8mm isotropic resolution.
  • Resting state fMRI (rfMRI) of 2mm isotropic resolution, multiband (MB) acceleration factor of 8, TR 720ms, acquired twice: once with AP and once with PA phase encoding.
  • Diffusion MRI (dMRI) 1.5mm isotropic, MB acceleration factor of 4, 92 directions in each shell (b=1500 and 3000) acquired twice: once with AP and once with PA phase encoding. In addition, field maps were acquired to correct for intensity and geometric distortions.

Download detailed protocols for all HCP-EP sites

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The Human Connectome Project and Connectome Coordination Facility are funded by the National Institutes of Health, and all information in this site is available to the public domain. No Protected Health Information has been published on this site.