An important objective of the Human Connectome Project is to identify functionally distinct subdivisions (parcels, or nodes) of the human brain and to understand the relationships among these parcels. Why is tas
Resting state functional MRI (R-fMRI) is a relatively new and powerful method for evaluating regional interactions that occur when a subject is not performing an explicit task. Low-frequency (<0.1 Hz) BOLD fluctuation
When acquiring diffusion data one typically acquires an image where each pixel has information about diffusion along one direction and for some range of diffusivities. The full data consists of a set of such measurements
MR diffusion tractography is a method for identifying anatomical connections in the living human brain. These connections form the substrate for information transfer between remote brain regions and are therefore central
Susceptibility artifact correction.Scanned objects have variable magnetic susceptibility, leading to a complex pattern of field inhomogeneities. These cause image distortions and dropout in most diffusion and fMRI acquis
Two groups of pulse sequences have revolutionized neuroimaging research, diffusion imaging and functional imaging (fMRI). Both rely on image formation via the echo planar imaging (EPI) pulse sequence. Figure 1:&nb
Cutting-edge MRI Hardware Technology. The HCP has developed customized MRI equipment to comfortably image the large subject population. All subjects in the main cohort are being scanned on a dedicated 3 Tesla (3T)
The Human Connectome Project will provide a treasure trove of information at an unprecedented level of detail. It is important that the interpretation of these connectivity data respects key organizational features
We plan a multi-track data acquisition strategy for optimal utilization of the equipment and the large subject population available to our consortium. During the optimization phase (Phase I, Fall 2010 - Spring 2
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